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Avanti NanoSciences Develops Technology for Rapid Endotoxin Management Products
Publish Date : 2/3/2007 10:18:00 AM   Source : Science News ExpressNewsline.com

Avanti NanoSciences, located in Baltimore, Maryland, is developing a portfolio of products for rapid, reagent-free detection and removal of endotoxins from biopharmaceutical products.

The Maryland bionanotechnology company is engaged in the development of a portfolio of products for the rapid reagent-free detection of microbes, viruses and microbial components based on its advanced, proprietary NanoBindiTM technology.

Avanti NanoSciences has two main areas of immediate application for which product ranges are being commercialized. Along with biopharmaceutical endotoxin removal and detection, the company is also developing food safety aspects of the technology.

In addition, the Maryland Company says its patent pending technology offers future opportunities in certain clinical therapeutic processes, biomarker monitoring, bio defense and food preservation.

Endotoxin is a potentially fatal pyrogen that may be present in injectable drugs and vaccines, medical devices and the water for injection systems found in the pharmaceutical industry. Many biopharmaceuticals which are produced by genetically engineered bacteria contain high levels of endotoxins in their raw form. For safety reasons all drugs must be cleaned of endotoxins in a specific purification process. Meanwhile, in cell based assays endotoxin contamination can greatly influence results.

In the area of biopharmaceuticals, the technology is applied in the detection and removal of endotoxins. Endotoxins are important in medicine and pharmacology as they are the major cause of sepsis in humans. The removal of these contaminants from the processes involved in developing and producing biopharmaceutical drugs is essential for the major pharmaceutical companies. The current product development portfolio includes EndoSneseTM for endotoxin detection, EndoStripTM for endotoxin removal and EndomonTM for real-time monitoring of endotoxins in pharmaceutical grade water purification.

Meanwhile, the food safety testing applications of the technology enable fast and reliable test procedures e.g. the testing of meat, seafood, milk or cheese for pathogenic organisms such as E. coli, Salmonella and Listeria which are major causes of food poisoning. Avanti NanoSciences intends to raise the capital to complete the existing product portfolios (including corresponding approvals) and to advance commercialization activities through further enhancement of sales and marketing functions.

About Avanti NanoSciences Avanti NanoSciences is the leader in the rapidly growing field of rapid detection and biomarker monitoring. Avanti's business is organized around two broad markets: Life Sciences and Industrial. The Company provides leading-edge products to meet the demanding needs of customers in biotechnology, pharmaceuticals, food safety, bionanotechnology, hospital acquired infections, bio defense and broad healthcare markets. The Company headquarters are in Baltimore, Maryland. Further information is available at http://www.anano.at-gc.com/

Contact Information: Jenny Smith Media Relations Avanti Therapeutics www.anano.at-c.com





Indo-Australia committed to resolve agri-trade issues         Publish Date : 3/3/2007 7:21:00 AM  
The agri-trade has become a very contentious issue in the World Trade Organisation (WTO), but India and Australia have agreed to resolve issues coming in the way of trade in agricultural goods by setting up a mechanism.

RBI to absorb more liquidity to contain inflation         Publish Date : 3/3/2007 7:11:00 AM  
In a bid to further contain inflation, Reserve Bank of India today announced a modified market stabilisation scheme (MSS) and liquidity adjustment facility (LAF) to suck out Rs 11,500 crore from the system.

Gold and Silver prices turn distinctly weak         Publish Date : 3/3/2007 7:03:00 AM  
Both the precious metals today turned distinctly weak on the bullion market as silver plunged by Rs 570 and gold by Rs 155 on heavy stockists offerings tiggered by sharp fall in the global markets.

Further fall in gold and silver prices         Publish Date : 3/2/2007 7:06:00 AM  
Both the precious metals continued to decline on the bullion market here today on sustained offering from stockists in view of fall in the international markets.

Rupee ends marginally up at 44.26/27 a dollar         Publish Date : 3/2/2007 7:03:00 AM  
The rupee today ended marginally higher at Rs 44.26/27 a dollar, supported by a smart recovery on equity markets coupled with fresh exporters' dollar sales.

Hyundai domestic sales up 74 pc in Feb         Publish Date : 3/2/2007 7:01:00 AM  
Hyundai Motor India today reported a 74 per cent increase in its domestic vehicle sales during February at 15,459 units compared to the same month last year.

Hutchison Telecom files caveat fearing legal move by Essar         Publish Date : 3/2/2007 6:59:00 AM  
Hong Kong-based Hutchison Telecom has filed a caveat before the Bombay High Court to ensure that its plea is heard in case Essar moves the court, challenging the the foreign partner's decision to sell stake to Vodafone.

Skoda slashes car prices up to Rs 24,000         Publish Date : 3/2/2007 6:56:00 AM  
As car makers Maruti and Hyundai announced a hike in prices, luxury car maker Skoda Auto today slashed prices across all models by up to Rs 24,000 citing reduction in customs duty on imported car parts in the Budget.

Bond prices continue to decline         Publish Date : 3/1/2007 8:30:00 AM  
Government bond prices continued to decline on persistent selling while call rates eased in view of ample liqudity in the system.

India should be more conscious of global developments: RBI         Publish Date : 3/1/2007 8:19:00 AM  
The Reserve Bank of India today said the steep fall in Indian stock markets was a contagious effect of plunge in overseas bourses and the country should have strong market and regulatory mechanism to avoid disruption in markets.

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