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Avanti NanoSciences Develops Technology for Rapid Endotoxin Management Products
Publish Date : 2/3/2007 10:18:00 AM   Source : Science News ExpressNewsline.com

Avanti NanoSciences, located in Baltimore, Maryland, is developing a portfolio of products for rapid, reagent-free detection and removal of endotoxins from biopharmaceutical products.

The Maryland bionanotechnology company is engaged in the development of a portfolio of products for the rapid reagent-free detection of microbes, viruses and microbial components based on its advanced, proprietary NanoBindiTM technology.

Avanti NanoSciences has two main areas of immediate application for which product ranges are being commercialized. Along with biopharmaceutical endotoxin removal and detection, the company is also developing food safety aspects of the technology.

In addition, the Maryland Company says its patent pending technology offers future opportunities in certain clinical therapeutic processes, biomarker monitoring, bio defense and food preservation.

Endotoxin is a potentially fatal pyrogen that may be present in injectable drugs and vaccines, medical devices and the water for injection systems found in the pharmaceutical industry. Many biopharmaceuticals which are produced by genetically engineered bacteria contain high levels of endotoxins in their raw form. For safety reasons all drugs must be cleaned of endotoxins in a specific purification process. Meanwhile, in cell based assays endotoxin contamination can greatly influence results.

In the area of biopharmaceuticals, the technology is applied in the detection and removal of endotoxins. Endotoxins are important in medicine and pharmacology as they are the major cause of sepsis in humans. The removal of these contaminants from the processes involved in developing and producing biopharmaceutical drugs is essential for the major pharmaceutical companies. The current product development portfolio includes EndoSneseTM for endotoxin detection, EndoStripTM for endotoxin removal and EndomonTM for real-time monitoring of endotoxins in pharmaceutical grade water purification.

Meanwhile, the food safety testing applications of the technology enable fast and reliable test procedures e.g. the testing of meat, seafood, milk or cheese for pathogenic organisms such as E. coli, Salmonella and Listeria which are major causes of food poisoning. Avanti NanoSciences intends to raise the capital to complete the existing product portfolios (including corresponding approvals) and to advance commercialization activities through further enhancement of sales and marketing functions.

About Avanti NanoSciences Avanti NanoSciences is the leader in the rapidly growing field of rapid detection and biomarker monitoring. Avanti's business is organized around two broad markets: Life Sciences and Industrial. The Company provides leading-edge products to meet the demanding needs of customers in biotechnology, pharmaceuticals, food safety, bionanotechnology, hospital acquired infections, bio defense and broad healthcare markets. The Company headquarters are in Baltimore, Maryland. Further information is available at http://www.anano.at-gc.com/

Contact Information: Jenny Smith Media Relations Avanti Therapeutics www.anano.at-c.com





Harvard students condemn Oxford University         Publish Date : 3/5/2007 7:11:00 AM  
Two Harvard students, including an NRI, have condemned Oxford University, where they are Rhodes scholars, as "outdated" and "frustrating" and dismissed its world famous Bodleian library as "less than inspiring".

Indian embassy to outsource jobs to American firm         Publish Date : 3/5/2007 7:10:00 AM  
After taking thousands of American jobs through outsourcing, India is planning to give a few back. The Indian embassy in the US capital is planning to outsource processing of visas to a US-based company.

Badal heads 18-member coalition ministry in Punjab(Final lead: Badal)         Publish Date : 3/3/2007 7:29:00 AM  
Octogenarian leader of the Shiromani Akali Dal (SAD) Parkash Singh Badal, on Friday took oath as Punjab's new Chief Minister and will lead an 18-member SAD-Bharatiya Janata Party (BJP) coalition ministry.

Bareilly eunuch adopts a girl child         Publish Date : 3/3/2007 7:22:00 AM  
It was a day of celebration for Saroj, a eunuch in Bareilly in Uttar Pradesh, as 'she' has become a 'mother' by adopting a baby girl.

Kalam offers prayer at Fatehpuri Masjid         Publish Date : 3/3/2007 7:16:00 AM  
Keeping a promise made two years ago, President A P J Abdul Kalam today offered prayers at the historic Fatehpuri Masjid in Chandni Chowk here along with thousands of Muslims.

Union Budget directionless, says Modi         Publish Date : 3/1/2007 8:41:00 AM  
Gujarat Chief Minister Narendra Modi today criticised the Union Budget by terming it as "directionless".

Centre allocates over Rs 100 crore for minority zones         Publish Date : 3/1/2007 8:38:00 AM  
Unfazed by the BJP's criticism over its welfare schemes for Muslims, the Congress-led Central Government has allocated over Rs 100 crore for development programmes in select districts with a sizeable population of minorities.

Kins of political bigwigs fail to find voters' favour         Publish Date : 3/1/2007 8:27:00 AM  
The assembly polls in Punjab turned out to be unkind for several kins of political bigwigs as voters rejected most of them barring some of Shiromani Akali Dal (SAD) supremo Parkash Singh Badal's near and dear ones.

High Court order on age of nursery admission tomorrow         Publish Date : 3/1/2007 8:24:00 AM  
The Delhi High Court today observed that the city Government's submission that a child should be four-years-old to get admission in nursery class was contrary to the law.

Parliament session may be stormy tomorrow on Quattrocchi issue         Publish Date : 3/1/2007 8:18:00 AM  
After the lull, it is going to be storm again in Parliament tomorrow.

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